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Synthesis Of Aspirin

Using Organic Chemistry, Can You Make Aspirin?

  • Classic AP Chemistry Experiment
  • Instructions Included
In a reaction vessel salicylic acid, acetic anhydride and sulfuric acid are mixed. The exothermic reaction will cause the temperature to increase to 70-80°C. Once the reaction is complete the vessel is cooled in an ice bath and the acetylsalicylic acid crystallizes out. This material is re-crystallized in toluene to purify the product. The product identity is confirmed by melting point. The mass of the re-crystallized product is used to determine the yield of the synthesis. In this experiment, we will perform the synthesis of acetylsalicylic acid (aspirin), purification by re-crystallization and use melting point to confirm identity.

Ordering information: Kit includes Acetic Anhydride, Salicylic Acid, Sulfuric Acid, and Toluene.



Item # Description No. of Lab Groups Unit Availability Price Quantity
470163-108 Synthesis of Aspirin
Hazardous Product
15 Kit of 1 Retrieving



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