Hands-on simulation of Sickle Cell diagnostic test.
- Perform a simulated test on a patient sample
- No actual blood or blood products are used.
- Includes all required reagents
- Use DNA Electrophoresis to reach a diagnosis
- Activity can be completed in 45 minutes
Sickle Cell Anemia is a common genetic disease that causes long rods in red blood cells, giving them a 'sickled' appearance. These cells get stuck in small capillaries of the blood stream leading to oxygen deprivation that causes pain and organ damage.
Sickle Cell Anemia is caused by a single point mutation in the hemoglobin gene that results in a faulty protein.
In this experiment, your students will investigate the restriction enzyme that discriminates between HbA (normal) and HbS (disease) genes and perform a simulated test on a patient.
Additional items needed but not included: DNA Electrophoresis equipment, White light box, microwave or hot plate.
Ordering information: Kit or Refill Set will ship immediately upon ordering. Please call to specify a future shipping date.
Caution: Store DNA samples in the refrigerator. All other components may be stored at room temperature.